Toronto at Chi. White Sox 2:10 PM ET
A 10-game winning streak has vaulted the Toronto Blue Jays to the top of the American League East standings while raising the club's confidence.
LA Dodgers at Milwaukee 2:10 PM ET
The struggling Los Angeles Dodgers are expected to turn to right-hander Tyler Glasnow as they look to avoid a series sweep against the host Milwaukee Brewers on Wednesday afternoon in the finale of a three-game set.
Philadelphia at San Francisco 3:45 PM ET
The San Francisco Giants will continue an improbable quest to nearly catch the first-place Los Angeles Dodgers before the All-Star break when the Giants go for a three-game sweep of the visiting Philadelphia Phillies on Wednesday afternoon.
Tampa Bay at Detroit 5:10 PM ET
The streaking Detroit Tigers can reach the 60-win mark as early as Wednesday when they host the Tampa Bay Rays.
Seattle at NY Yankees 7:05 PM ET
After a week of angst that saw them fall out of first place in the American League East, the New York Yankees enjoyed a big night at the plate and their pitching held up on Tuesday.
Colorado at Boston 7:10 PM ET
Masataka Yoshida is expected to be in the lineup when the Boston Red Sox try to complete a three-game sweep of the visiting Colorado Rockies on Wednesday.
Miami at Cincinnati 7:10 PM ET
Andrew Abbott thought he'd be showing the rest of the National League what they'd be missing when he takes the mound for the Cincinnati Reds in the third game of their four-game series against the visiting Miami Marlins on Wednesday night.
Pittsburgh at Kansas City 7:40 PM ET
Left-hander Kris Bubic is headed to his first All-Star Game next week, but he hasn't been sharp of late for the Kansas City Royals.
Chi. Cubs at Minnesota 7:40 PM ET
The Minnesota Twins enjoyed a near-perfect series opener against the Chicago Cubs.
Washington at St. Louis 7:45 PM ET
After replacing Washington Nationals manager Dave Martinez on an interim basis, Miguel Cairo will try to guide this re-tooling team onto a positive track.
Cleveland at Houston 8:10 PM ET
With Houston closer Josh Hader having last worked on Saturday and the Astros set for an off day on Thursday, manager Joe Espada opted to send his All-Star reliever back out for a second inning of work in the top of the 10th against the Cleveland Guardians on Tuesday.
Texas at LA Angels 9:38 PM ET
Right-hander Kumar Rocker will face the team he defeated for his first major league win earlier this season when the Texas Rangers continue their four-game series with the Los Angeles Angels on Wednesday night in Anaheim, Calif.
Arizona at San Diego 9:40 PM ET
Tuesday was a big day for San Diego Padres closer Robert Suarez.
Atlanta at Athletics 10:05 PM ET
The Atlanta Braves were crushed in their series opener against the Athletics, but overshadowing the beatdown was the absence of star right fielder Ronald Acuna Jr.